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产品信息
ABS 039-32B-005
产品规格
种属反应
Rat
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
32
抗原
Recombinant rat NGAL precursor.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
purified
保存液
PBS, pH 7.4
内含物
15mM sodium azide
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_1076452
产品详细信息
ABS 039-32B-005 detects NGAL in rat samples. This antibody will not cross react with human, pig, dog, or mouse NGAL.
ABS 039-32B-005 has been successfully used in ELISA procedures.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
靶标信息
NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; HGNC:6526; lipocalin 2 (oncogene 24p3); Lipocalin 24p3; Lipocalin-2; Lipocalin2; Neutrophil gelatinase-associated lipocalin; NGAL; OTTHUMP00000022240; p25; RP23-161B9.11; Siderocalin LCN2; uterocalin
基因别名: Lcn2; Sip24
UniProt ID: (Rat) P30152
Entrez Gene ID: (Rat) 170496
ion transport
response to oxidative stress
response to virus
response to bacterium
response to herbicide
response to mycotoxin
positive regulation of gene expression
siderophore transport
positive regulation of cell projection organization
response to nutrient levels
cellular response to nutrient levels
response to drug
innate immune response
iron ion homeostasis
protein homotrimerization
cellular response to hydrogen peroxide
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
extrinsic apoptotic signaling pathway in absence of ligand
